Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects

Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects

Release of insect pests carrying the dominant lethal tetracycline transactivator (tTA) overexpression system has been proposed as a means for population suppression. High levels of the tTA transcription factor are thought to be toxic due to either transcriptional squelching or interference with prot...

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Bibliographic Details
Main Authors: Katherine E. Knudsen, William R. Reid, Traci M. Barbour, Laci M. Bowes, Juliana Duncan, Elaina Philpott, Samantha Potter, Maxwell J. Scott
Format: Article
Language:English
Published: Oxford University Press 2020-04-01
Series:G3: Genes, Genomes, Genetics
Subjects:
dgrp
fs-ridl
sterile insect technique
tetracycline transactivator
male-only strain
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.400990

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http://g3journal.org/lookup/doi/10.1534/g3.120.400990

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