MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling

Cardiovascular diseases (CVDs) are a major cause of death worldwide. Due to the prevalence of many side effects and incomplete recovery from pharmacotherapies, stem cell therapy is being targeted for the treatment of CVDs. Among the different types of stem cells, endothelial progenitor cells (EPCs)...

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Main Authors: Shreekrishna Lamichane, Sang Hong Baek, Yeon-Ju Kim, Ji Hye Park, Babita Dahal Lamichane, Woong Bi Jang, SeungTaek Ji, Na Kyung Lee, Li Dehua, Da Yeon Kim, Songhwa Kang, Ha Jong Seong, Jisoo Yun, Dong Hyung Lee, Hyung Ryong Moon, Hae Young Chung, Sang-Mo Kwon
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/6492029