Neonatal Clonazepam Administration Induced Long-Lasting Changes in GABA<sub>A</sub> and GABA<sub>B</sub> Receptors

Neonatal Clonazepam Administration Induced Long-Lasting Changes in GABA<sub>A</sub> and GABA<sub>B</sub> Receptors

Benzodiazepines (BZDs) are widely used in patients of all ages. Unlike adults, neonatal animals treated with BZDs exhibit a variety of behavioral deficits later in life; however, the mechanisms underlying these deficits are poorly understood. This study aims to examine whether administration of clon...

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Bibliographic Details
Main Authors: Hana Kubová, Zdeňka Bendová, Simona Moravcová, Dominika Pačesová, Luisa Rocha, Pavel Mareš
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
neonatal rat
clonazepam
GABA<sub>A</sub>/BZD receptor binding
GABA<sub>B</sub> receptor binding
subunit mRNA expression
Online Access:https://www.mdpi.com/1422-0067/21/9/3184

Internet

https://www.mdpi.com/1422-0067/21/9/3184

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