Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing
Diabetic foot ulcers (DFU) represent a complex disease with limited treatment options. Here, the authors compare human RNASeq patient data from DFU, oral mucosa and skin acute wounds, identifying FOXM1 as a mediator of macrophage and neutrophil recruitment, which contributes to disease pathogenesis...
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Bibliographic Details
| Main Authors: |
Andrew P. Sawaya,
Rivka C. Stone,
Stephen R. Brooks,
Irena Pastar,
Ivan Jozic,
Kowser Hasneen,
Katelyn O’Neill,
Spencer Mehdizadeh,
Cheyanne R. Head,
Natasa Strbo,
Maria I. Morasso,
Marjana Tomic-Canic |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-09-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-18276-0
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