Effect of Scrapie Prion Infection in Ovine Bone Marrow-Derived Mesenchymal Stem Cells and Ovine Mesenchymal Stem Cell-Derived Neurons

Effect of Scrapie Prion Infection in Ovine Bone Marrow-Derived Mesenchymal Stem Cells and Ovine Mesenchymal Stem Cell-Derived Neurons

Scrapie is a prion disease affecting sheep and goats and it is considered a prototype of transmissible spongiform encephalopathies (TSEs). Mesenchymal stem cells (MSCs) have been proposed as candidates for developing in vitro models of prion diseases. Murine MSCs are able to propagate prions after p...

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Bibliographic Details
Main Authors: Laura García-Mendívil, Diego R. Mediano, Adelaida Hernaiz, David Sanz-Rubio, Francisco J. Vázquez, Belén Marín, Óscar López-Pérez, Alicia Otero, Juan J. Badiola, Pilar Zaragoza, Laura Ordovás, Rosa Bolea, Inmaculada Martín-Burriel
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Animals
Subjects:
scrapie
prion
sheep
infection
mesenchymal stem cell
in vitro model
Online Access:https://www.mdpi.com/2076-2615/11/4/1137

Internet

https://www.mdpi.com/2076-2615/11/4/1137

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