Trophic factors as modulators of motor neuron physiology and survival: implications for ALS therapy

Trophic factors as modulators of motor neuron physiology and survival: implications for ALS therapy

Motor neuron physiology and development depend on a continuous and tightly regulated trophic support from a variety of cellular sources. Trophic factors guide the generation and positioning of motor neurons during every stage of the developmental process. As well, they are involved in axon guidance...

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Bibliographic Details
Main Authors: Luis B Tovar-y-Romo, Uri Nimrod Ramírez-Jarquín, Rafael eLazo-Gómez, Ricardo eTapia
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Amyotrophic Lateral Sclerosis
Motor Neurons
VEGF
neurotrophic factors
spinal cord neurodegeneration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00061/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00061/full

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