Correlation between Family RB1 Gene Pathogenic Variant with Clinical Features and Prognosis of Retinoblastoma under 5 Years Old

Retinoblastoma (RB) is the most common primary intraocular malignant tumor in infants and the prototype of human hereditary tumors. Its occurrence and development are closely related to the pathogenic variant of tumor suppressor RB1 gene. We aim to analyze the characteristics of RB1 gene pathogenic...

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Bibliographic Details
Main Authors: Yi Zhang, Yizhuo Wang, Dongsheng Huang, Jianmin Ma, Weiling Zhang, Huali Gu, Yan Zhou, You Yi, Pinwei Zhang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2021/9981028