Heterogeneous GABAA receptor subunit expression in pediatric epilepsy patients

Heterogeneous GABAA receptor subunit expression in pediatric epilepsy patients

The γ-amino-butyric acid type A receptors (GABAAR) are a heteropentameric receptor complex, composed of 16 possible subunits in various combinations, forming a ligand-gated ion channel. Subunit composition is the primary determinant of GABAAR physiology and pharmacology. Here we have measured mRNA l...

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Bibliographic Details
Main Authors: Brenda E. Porter, Guojun Zhang, Juanita Celix, Fu-chun Hsu, YogendraSinh H. Raol, Albert Telfeian, Paul R. Gallagher, Douglas A. Coulter, Amy R. Brooks-Kayal
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neurobiology of Disease
Subjects:
Epilepsy
γ-Amino-butyric acid receptor
Dentate granule neurons
Pediatrics
Pharmacogenomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104003213

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http://www.sciencedirect.com/science/article/pii/S0969996104003213

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