Gene-gene and gene-environment interactions in meta-analysis of genetic association studies.

Extensive genetic studies have identified a large number of causal genetic variations in many human phenotypes; however, these could not completely explain heritability in complex diseases. Some researchers have proposed that the "missing heritability" may be attributable to gene-gene and...

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Bibliographic Details
Main Authors: Chin Lin, Chi-Ming Chu, John Lin, Hsin-Yi Yang, Sui-Lung Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414456?pdf=render