PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

<p>Abstract</p> <p>Background</p> <p>Angiotensin II (Ang II) signaling occurs via two major receptors which activate non-receptor tyrosin kinases that then interact with protein tyrosin-phosphatases (PTPs) to regulate cell function. SHP-2 is one such important PTP that...

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Bibliographic Details
Main Authors: Rossi Gian, Dal Maso Lucia, Pagnin Elisa, Davis Paul A, Bordin Luciana, Calò Lorenzo A, Pessina Achille C, Clari Giulio
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Journal of Biomedical Science
Subjects:
Angiotensin II signaling
SHP-2
PLCβ1
SHP-2-PLCβ1 complex
Online Access:http://www.jbiomedsci.com/content/18/1/38

Internet

http://www.jbiomedsci.com/content/18/1/38

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