Co-lethality studied as an asset against viral drug escape: the HIV protease case

<p>Abstract</p> <p>Background</p> <p>Co-lethality, or synthetic lethality is the documented genetic situation where two, separately non-lethal mutations, become lethal when combined in one genome. Each mutation is called a "synthetic lethal" (SL) or a co-letha...

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Bibliographic Details
Main Authors: Ollivier Emmanuelle, Valere Thomas, Brouillet Sophie, Marsan Laurent, Vanet Anne
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/5/1/40