Tempol Supplementation Restores Diaphragm Force and Metabolic Enzyme Activities in mdx Mice

Duchenne muscular dystrophy (DMD) is characterized by striated muscle weakness, cardiomyopathy, and respiratory failure. Since oxidative stress is recognized as a secondary pathology in DMD, the efficacy of antioxidant intervention, using the superoxide scavenger tempol, was examined on functional a...

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Bibliographic Details
Main Authors: David P. Burns, Izza Ali, Clement Rieux, James Healy, Greg Jasionek, Ken D. O’Halloran
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Antioxidants
Subjects:
mdx
Online Access:https://www.mdpi.com/2076-3921/6/4/101