Limitations of lymphoblastoid cell lines for functional analysis of SNPs

Abstract Objective Single nucleotide polymorphisms (SNPs) are widely linked to the susceptibility and penetrance of diseases. SNP rs886205 (A/G) located in the aldehyde dehydrogenase 2 (ALDH2) promoter is associated with esophageal carcinoma in alcohol-dependent patients. Previously, we found an int...

Full description

Bibliographic Details
Main Authors: Hansi Pathak, Helge Frieling, Mathias Rhein, Alexandra Burkert
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Research Notes
Subjects:
SNP
Online Access:http://link.springer.com/article/10.1186/s13104-017-2864-6