Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive Salmonella isolates from Africa.

The various sub-species of Salmonella enterica cause a range of disease in human hosts. The human-adapted Salmonella enterica serovar Typhi enters the gastrointestinal tract and invades systemic sites to cause enteric (typhoid) fever. In contrast, most non-typhoidal serovars of Salmonella are primar...

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Bibliographic Details
Main Authors: Jared D Honeycutt, Nicolas Wenner, Yan Li, Susan M Brewer, Liliana M Massis, Sky W Brubaker, Phoom Chairatana, Siân V Owen, Rocío Canals, Jay C D Hinton, Denise M Monack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008763