TRPA1 Promotes Cardiac Myofibroblast Transdifferentiation after Myocardial Infarction Injury via the Calcineurin-NFAT-DYRK1A Signaling Pathway

TRPA1 Promotes Cardiac Myofibroblast Transdifferentiation after Myocardial Infarction Injury via the Calcineurin-NFAT-DYRK1A Signaling Pathway

Cardiac fibroblasts (CFs) are a critical cell population responsible for myocardial extracellular matrix homeostasis. After stimulation by myocardial infarction (MI), CFs transdifferentiate into cardiac myofibroblasts (CMFs) and play a fundamental role in the fibrotic healing response. Transient rec...

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Bibliographic Details
Main Authors: Shuang Li, Xiongshan Sun, Hao Wu, Peng Yu, Xin Wang, Zhenhua Jiang, Erhe Gao, Jiangwei Chen, De Li, Chenming Qiu, Baomei Song, Ken Chen, Kecheng He, Dachun Yang, Yongjian Yang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/6408352

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http://dx.doi.org/10.1155/2019/6408352

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