Statistical methods for quantitative mass spectrometry proteomic experiments with labeling

Statistical methods for quantitative mass spectrometry proteomic experiments with labeling

<p>Abstract</p> <p>Mass Spectrometry utilizing labeling allows multiple specimens to be subjected to mass spectrometry simultaneously. As a result, between-experiment variability is reduced. Here we describe use of fundamental concepts of statistical experimental design in the labe...

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Bibliographic Details
Main Authors: Oberg Ann L, Mahoney Douglas W
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Bioinformatics
Subjects:
mass spectrometry
experimental design
quality control
normalization
variance structure
labeling
iTRAQ
relative quantification
Online Access:http://www.biomedcentral.com/1471-2105/13/S16/S7

Internet

http://www.biomedcentral.com/1471-2105/13/S16/S7

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