Efficacy, safety and cost-effectiveness of a web-based platform delivering the results of a biomarker-based predictive model of biotherapy response for rheumatoid arthritis patients: a protocol for a randomized multicenter single-blind active controlled clinical trial (PREDIRA)

Efficacy, safety and cost-effectiveness of a web-based platform delivering the results of a biomarker-based predictive model of biotherapy response for rheumatoid arthritis patients: a protocol for a randomized multicenter single-blind active controlled clinical trial (PREDIRA)

Abstract Background Rheumatoid arthritis (RA) is one of the leading chronic inflammatory rheumatism. First-line therapy with synthetic disease-modifying antirheumatic drugs (sDMARD) is insufficiently effective in 40% of cases and these patients are treated with biotherapies. The increased use of the...

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Bibliographic Details
Main Authors: Dalifer Freites-Núñez, Athan Baillet, Luis Rodriguez-Rodriguez, Minh Vu Chuong Nguyen, Isidoro Gonzalez, Jose Luis Pablos, Alejandro Balsa, Monica Vazquez, Philippe Gaudin, Benjamín Fernandez-Gutierrez
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Trials
Subjects:
Rheumatoid arthritis
Personalized medicine
Prediction models
Anti-TNFα agents
Online Access:http://link.springer.com/article/10.1186/s13063-020-04683-7

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http://link.springer.com/article/10.1186/s13063-020-04683-7

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