Synthesis and Cytotoxic Activity of Biphenylurea Derivatives Containing Indolin-2-one Moieties

In our endeavor towards the development of potent anticancer agents, two different sets of biphenylurea-indolinone conjugates, 5a–s and 8a,b were synthesized. The in vitro cytotoxicity of the synthesized compounds was examined in two human cancer cell lines, namely MCF-7 breast cancer and PC-3 prost...

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Bibliographic Details
Main Authors: Wagdy M. Eldehna, Mohamed Fares, Hany S. Ibrahim, Muhammad A. Alsherbiny, Mohamed H. Aly, Hazem A. Ghabbour, Hatem A. Abdel-Aziz
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/6/762