Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex

The identification of protein-protein interaction disruptors (PPIDs) that disrupt the YAP/TAZ-TEAD interaction has gained considerable momentum. Several studies have shown that YAP/TAZ are no longer oncogenic when their interaction with the TEAD family of transcription factors is disrupted. The tran...

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Bibliographic Details
Main Authors: Ajaybabu V. Pobbati, Brian P. Rubin
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
YAP
TAZ
Online Access:https://www.mdpi.com/1420-3049/25/24/6001