The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation

<p>Mitochondria are the major reactive oxygen species (ROS) &#8211; generating sites in mammalian cells. Blockade of complexes in the electron transport chain (ETC) increases the leakage of single electrons to O<sub>2</sub> and therefore increases ROS levels. Complexes I and II...

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Bibliographic Details
Main Author: Jun Panee, Wanyu Liu, Kyoko Nakamura, Marla J. Berry
Format: Article
Language:English
Published: Ivyspring International Publisher 2007-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v03p0335.htm