Reprogramming Tumor Associated Macrophage Phenotype by a Polysaccharide from <i>Ilex asprella</i> for Sarcoma Immunotherapy

Reprogramming Tumor Associated Macrophage Phenotype by a Polysaccharide from <i>Ilex asprella</i> for Sarcoma Immunotherapy

We report here the discovery of an acidic polysaccharide, namely IAPS-2, from the root of <i>Ilex asprella</i>, with anti-tumor activity via a repolarizing tumor associated macrophages (TAMs) phenotype. We obtained IAPS-2 polysaccharide from this herb based on acidity and found that IAPS...

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Bibliographic Details
Main Authors: Qiu Li, Zhihui Hao, Yeting Hong, Wei He, Wenwen Zhao
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
IAPS-2 polysaccharide
repolarizing TAMs
cancer immunotherapy
Online Access:https://www.mdpi.com/1422-0067/19/12/3816

Internet

https://www.mdpi.com/1422-0067/19/12/3816

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