<i>N</i>-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—the Synthesis and Biological Evaluation of Enantiomers

<i>N</i>-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—the Synthesis and Biological Evaluation of Enantiomers

Tuberculosis is an infectious disease caused by <i>Mycobacterium tuberculosis</i> (Mtb), each year causing millions of deaths. In this article, we present the synthesis and biological evaluations of new potential antimycobacterial compounds containing a fragment of the first-line antitub...

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Bibliographic Details
Main Authors: Martin Juhás, Lucie Kučerová, Ondřej Horáček, Ondřej Janďourek, Vladimír Kubíček, Klára Konečná, Radim Kučera, Pavel Bárta, Jiří Janoušek, Pavla Paterová, Jiří Kuneš, Martin Doležal, Jan Zitko
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
amino acids
antibacterial
antimycobacterial
cytotoxicity
pyrazinamide
tuberculosis
Online Access:https://www.mdpi.com/1420-3049/25/7/1518

Internet

https://www.mdpi.com/1420-3049/25/7/1518

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