Establishment of mouse teratocarcinomas stem cells line and screening genes responsible for malignancy.

The sequential transplantation of embryonal carcinoma cells in vivo can accelerate the growth and malignancy of teratocarcinomas. However, the possible molecular mechanisms in this process that reflect cancer formation in the early stage are largely unknown and. To identify which genes are associate...

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Bibliographic Details
Main Authors: Tao Liu, Ying Wang, Xinrong Peng, Liqing Zhang, Jingbo Cheng, Huajun Jin, Mengchao Wu, Qijun Qian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432059?pdf=render