miR-21 Promotes Human Nucleus Pulposus Cell Proliferation through PTEN/AKT Signaling

miR-21 Promotes Human Nucleus Pulposus Cell Proliferation through PTEN/AKT Signaling

The precise role of nucleus pulposus cell proliferation in the pathogenesis of intervertebral disc degeneration remains to be elucidated. Recent findings have revealed that microRNAs, a class of small noncoding RNAs, may regulate cell proliferation in many pathological conditions. Here, we showed th...

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Bibliographic Details
Main Authors: Hongzhe Liu, Xiangwang Huang, Xiangyang Liu, Sheng Xiao, Yi Zhang, Tiecheng Xiang, Xiongjie Shen, Guoping Wang, Bin Sheng
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:International Journal of Molecular Sciences
Subjects:
disc degeneration
nucleus pulposus cells
miRNA
miR-21
proliferation
Online Access:http://www.mdpi.com/1422-0067/15/3/4007

Internet

http://www.mdpi.com/1422-0067/15/3/4007

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