Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism

Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism

Variations in the gene LDAH (C2ORF43), which encodes lipid droplet-associated hydrolase (LDAH), are among few loci associated with human prostate cancer. Homologs of LDAH have been identified as proteins of lipid droplets (LDs). LDs are cellular organelles that store neutral lipids, such as triacylg...

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Bibliographic Details
Main Authors: Nora Kory, Susanne Grond, Siddhesh S. Kamat, Zhihuan Li, Natalie Krahmer, Chandramohan Chitraju, Ping Zhou, Florian Fröhlich, Ivana Semova, Christer Ejsing, Rudolf Zechner, Benjamin F. Cravatt, Robert V. Farese, Jr., Tobias C. Walther
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Lipid Research
Subjects:
lipase
lipoprotein metabolism
cholesterol efflux
triglycerides
animal models
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314504

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http://www.sciencedirect.com/science/article/pii/S0022227520314504

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