Targeting amine- and phenol-containing metabolites in urine by dansylation isotope labeling and liquid chromatography mass spectrometry for evaluation of bladder cancer biomarkers

Metabolomics is considered an effective approach for understanding metabolic responses in complex biological systems. Accordingly, it has attracted increasing attention for biomarker discovery, especially in cancer. In this study, we used a non-invasive method to evaluate four urine metabolite bioma...

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Bibliographic Details
Main Authors: Yi-Ting Chen, Hsin-Chien Huang, Ya-Ju Hsieh, Shu-Hsuan Fu, Liang Li, Chien-Lun Chen, Lichieh Julie Chu, Jau-Song Yu
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Journal of Food and Drug Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949818301790