Role of the atypical vesicular glutamate transporter VGLUT3 in l-DOPA-induced dyskinesia

Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons. The gold standard therapy relies on dopamine (DA) replacement by the administration of levodopa (l-DOPA). However, with time l-DOPA treatment induces severe motor side effects characterized by abnormal and in...

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Bibliographic Details
Main Authors: Giuseppe Gangarossa, Monica Guzman, Vania F. Prado, Marco A.M. Prado, Stephanie Daumas, Salah El Mestikawy, Emmanuel Valjent
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611530111X