Peripheral Deltorphin II Inhibits Nociceptors Following Nerve Injury

Peripheral Deltorphin II Inhibits Nociceptors Following Nerve Injury

Clinical and preclinical studies have revealed that local administration of opioid agonists into peripheral tissue attenuates inflammatory pain. However, few studies have examined whether peripherally restricted opioids are effective in reducing mechanical allodynia and hyperalgesia that usually fol...

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Bibliographic Details
Main Authors: Marek Joukal, Lucy Vulchanova, Cecilia Huffman, Petr Dubový, Christopher N. Honda
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
nociceptors
spared nerve injury
delta opioid receptors
neuropathic pain
deltorphin II
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01151/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01151/full

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