Immunological relevance of the coevolution of IDO1 and AHR

The Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor initially identified because of its role in controlling the cellular response to environmental molecules. More recently, AHR has been shown to play a crucial role in controlling innate and adaptive immune responses throug...

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Bibliographic Details
Main Authors: Francisco Javier Quintana, Merja eJaronen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Immunology
Subjects:
IDO
AhR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00521/full