Structural insights of the ssDNA binding site in the multifunctional endonuclease AtBFN2 from Arabidopsis thaliana.

Structural insights of the ssDNA binding site in the multifunctional endonuclease AtBFN2 from Arabidopsis thaliana.

The multi S1/P1 nuclease AtBFN2 (EC 3.1.30.1) encoded by the Arabidopsis thaliana At1g68290 gene is a glycoprotein that digests RNA, ssDNA, and dsDNA. AtBFN2 depends on three zinc ions for cleaving DNA and RNA at 3'-OH to yield 5'-nucleotides. In addition, AtBFN2's enzymatic activity...

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Bibliographic Details
Main Authors: Tsung-Fu Yu, Manuel Maestre-Reyna, Chia-Yun Ko, Tzu-Ping Ko, Yuh-Ju Sun, Tsai-Yun Lin, Jei-Fu Shaw, Andrew H-J Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4144908?pdf=render

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http://europepmc.org/articles/PMC4144908?pdf=render

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