Role of Transglutaminase 2 in Cell Death, Survival, and Fibrosis

Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme catalyzing the crosslinking between Gln and Lys residues and involved in various pathophysiological events. Besides this crosslinking activity, TG2 functions as a deamidase, GTPase, isopeptidase, adapter/scaffold, protein disulfide isomeras...

Full description

Bibliographic Details
Main Authors: Hideki Tatsukawa, Kiyotaka Hitomi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
TG2
Online Access:https://www.mdpi.com/2073-4409/10/7/1842