Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome

Abstract Knowledge of the Plasmodium falciparum antigens that comprise the human liver stage immunoproteome is important for pre-erythrocytic vaccine development, but, compared with the erythrocytic stage immunoproteome, more challenging to classify. Previous studies of P. falciparum antibody respon...

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Bibliographic Details
Main Authors: Andrea A. Berry, Joshua M. Obiero, Mark A. Travassos, Amed Ouattara, Drissa Coulibaly, Matthew Adams, Rafael Ramiro de Assis, Aarti Jain, Omid Taghavian, Andrew Sy, Rie Nakajima, Algis Jasinskas, Matthew B. Laurens, Shannon Takala-Harrison, Bourema Kouriba, Abdoulaye K. Kone, Ogobara K. Doumbo, B. Kim Lee Sim, Stephen L. Hoffman, Christopher V. Plowe, Mahamadou A. Thera, Philip L. Felgner, Kirsten E. Lyke
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00363-y