Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography

Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography

The control of DNA-mediated assembly depends on a precise understanding of the three-dimensional structure of DNA-nanocrystal-hybridized building blocks. Here, the authors use cryo-electron microscopy and negative-staining techniques to investigate the morphology of DNA-nanogold conjugates.

Bibliographic Details
Main Authors: Lei Zhang, Dongsheng Lei, Jessica M. Smith, Meng Zhang, Huimin Tong, Xing Zhang, Zhuoyang Lu, Jiankang Liu, A. Paul Alivisatos, Gang Ren
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11083

Internet

https://doi.org/10.1038/ncomms11083

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