Enteral administration of bacteria fermented formula in newborn piglets: A high fidelity model for necrotizing enterocolitis (NEC).

OBJECTIVE:To develop an animal model which replicates neonatal NEC and characterizes the importance of bacterial fermentation of formula and short chain fatty acids (SCFAs) in its pathogenesis. BACKGROUND:NEC is a severe form of intestinal inflammation in preterm neonates and current models do not r...

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Bibliographic Details
Main Authors: Shreyas K Roy, Qinghe Meng, Benjamin D Sadowitz, Michaela Kollisch-Singule, Natesh Yepuri, Joshua Satalin, Louis A Gatto, Gary F Nieman, Robert N Cooney, David Clark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6056052?pdf=render