The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia

Abstract Using genome-wide transcriptome analysis by RNA sequencing of first trimester plasma RNA, we tested whether the identification of pregnancies at risk of developing pre-eclampsia with or without preterm birth or growth restriction is possible between weeks 9–14, prior to the appearance of cl...

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Bibliographic Details
Main Authors: Vera Manders, Allerdien Visser, Remco Keijser, Naomi Min, Ankie Poutsma, Joyce Mulders, Tarah van den Berkmortel, Marjolein Hortensius, Aldo Jongejan, Eva Pajkrt, Erik A. Sistermans, Daoud Sie, Myron G. Best, Tom Würdinger, Marjon de Boer, Gijs Afink, Cees Oudejans
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79008-4