ATP-Dependent Persister Formation in Escherichia coli
Persisters are dormant variants that form a subpopulation of cells tolerant to antibiotics. Persisters are largely responsible for the recalcitrance of chronic infections to therapy. In Escherichia coli, one widely accepted model of persister formation holds that stochastic accumulation of ppGpp cau...
Main Authors: | Yue Shan, Autumn Brown Gandt, Sarah E. Rowe, Julia P. Deisinger, Brian P. Conlon, Kim Lewis, Karen Bush |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-02-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/1/e02267-16 |
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