Acid bone lysate activates TGFβ signalling in human oral fibroblasts

Acid bone lysate activates TGFβ signalling in human oral fibroblasts

Abstract Demineralized bone matrix is a widely used allograft from which not only the inorganic mineral but also embedded growth factors are removed by hydrochloric acid (HCl). The cellular response to the growth factors released during the preparation of demineralized bone matrix, however, has not...

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Bibliographic Details
Main Authors: Franz Josef Strauss, Alexandra Stähli, Lucian Beer, Goran Mitulović, Valentina Gilmozzi, Nina Haspel, Gerhild Schwab, Reinhard Gruber
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Oral Fibroblasts
TGFβ Signaling
Demineralized Bone Matrix
NADPH Oxidase (NOX4)
Bone Chips
Online Access:https://doi.org/10.1038/s41598-018-34418-3

Internet

https://doi.org/10.1038/s41598-018-34418-3

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