Yeast Model Uncovers Dual Roles of Mitochondria in the Action of Artemisinin.

Artemisinins, derived from the wormwood herb Artemisia annua, are the most potent antimalarial drugs currently available. Despite extensive research, the exact mode of action of artemisinins has not been established. Here we use yeast, Saccharamyces cerevisiae, to probe the core working mechanism of...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-09-01
Series:PLoS Genetics
Online Access:http://dx.doi.org/10.1371/journal.pgen.0010036