Effectiveness of 4-1BB-costimulated HER2-targeted chimeric antigen receptor T cell therapy for synovial sarcoma

Effectiveness of 4-1BB-costimulated HER2-targeted chimeric antigen receptor T cell therapy for synovial sarcoma

Background: Synovial sarcoma is a rare malignant soft-tissue tumor that is prevalent in adolescents and young adults, and poor prognosis has been reported in patients with metastatic lesions. Chimeric antigen receptor (CAR) T-cell therapy is an emerging novel therapy for solid tumors; however, its a...

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Bibliographic Details
Main Authors: Yudai Murayama, Hiroyuki Kawashima, Nobuhiro Kubo, Chansu Shin, Yasushi Kasahara, Masaru Imamura, Naoki Oike, Takashi Ariizumi, Akihiko Saitoh, Keichiro Mihara, Hajime Umezu, Akira Ogose, Chihaya Imai
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Translational Oncology
Subjects:
Synovial sarcoma
HER2
Chimeric antigen receptor
T cell
Cancer immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321002199

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http://www.sciencedirect.com/science/article/pii/S1936523321002199

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