Research on the Species Difference of the Hepatotoxicity of Medicine Based on Transcriptome

In recent years, several drugs have been withdrawn from use by regulatory bodies owing to hepatotoxicity; therefore, studies on drug-induced liver injury (DILI) are being actively pursued. Most studies evaluating DILI use rats or mice as animal models to determine drug toxicity; however, the toxicit...

Full description

Bibliographic Details
Main Authors: Ziying Xu, Qianjun Kang, Zihui Yu, Lichun Tian, Jingxuan Zhang, Ting Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.647084/full