Hypoxia as a Stimulus for the Maturation of Meniscal Cells: Highway to Novel Tissue Engineering Strategies?

Hypoxia as a Stimulus for the Maturation of Meniscal Cells: Highway to Novel Tissue Engineering Strategies?

The meniscus possesses low self-healing properties. A perfect regenerative technique for this tissue has not yet been developed. This work aims to evaluate the role of hypoxia in meniscal development in vitro. Menisci from neonatal pigs (day 0) were harvested and cultured under two different atmosph...

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Bibliographic Details
Main Authors: Valentina Rafaela Herrera Millar, Laura Mangiavini, Umberto Polito, Barbara Canciani, Van Thi Nguyen, Federica Cirillo, Luigi Anastasia, Giuseppe Maria Peretti, Silvia Clotilde Modina, Alessia Di Giancamillo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
glycosaminoglycans
HIF-1α
hypoxia
meniscus
pig
fibro-chondrocytes
Online Access:https://www.mdpi.com/1422-0067/22/13/6905

Internet

https://www.mdpi.com/1422-0067/22/13/6905

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