TGFβ-signaling in Squamous Cell Carcinoma Occurring in Recessive Dystrophic Epidermolysis Bullosa

Background: Recessive dystrophic epidermolysis bullosa (RDEB) is a hereditary skin disorder characterized by mechanical fragility of the skin, resulting in blistering and chronic wounds. The causative mutations lie in the COL7A1 gene. Patients suffering from RDEB have a high risk to develop aggressi...

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Bibliographic Details
Main Authors: Julia Knaup, Christina Gruber, Barbara Krammer, Verena Ziegler, Johann Bauer, Thomas Verwanger
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2011-0039