Impact of MTHFR (C677T) gene polymorphism on antiepileptic drug monotherapy in North Indian epileptic population

BACKGROUND AND OBJECTIVES: Antiepileptic drugs (AEDs) are known to interfere with homocysteine metabolism. Hyperhomocysteinemia may be a risk factor associated in the long-term treatment with AEDs. Both genetic and non-genetic factors are responsible for hyperhomocysteinemia. MTHFR C677T. Polymorphi...

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Bibliographic Details
Main Authors: Murali Munisamy, Mubarak Al-Gahtany, Manjari Tripathi, Vivekanandhan Subbiah
Format: Article
Language:English
Published: King Faisal Specialist Hospital and Research Centre 2015-01-01
Series:Annals of Saudi Medicine
Online Access:https://www.annsaudimed.net/doi/full/10.5144/0256-4947.2015.51