An osteogenic helioxanthin derivative suppresses the formation of bone-resorbing osteoclasts

Objective: The helioxanthin derivative 4-(4-methoxyphenyl)thieno[2,3-b:5,4-c′]dipyridine-2-carboxamide (TH) is a low-molecular-weight compound that was identified through screening for osteogenic compounds that enhance the activity of mouse preosteoblastic MC3T3-E1 cells. In the present study, we fo...

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Bibliographic Details
Main Authors: Hitoshi Amano, Futoshi Iwaki, Meiko Oki, Kazuhiro Aoki, Shinsuke Ohba
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S235232041930077X