Matricryptins network with matricellular receptors at the surface of endothelial and tumor cells
The extracellular matrix is a source of bioactive fragments called matricryptins or matrikines resulting from the proteolytic cleavage of extracellular proteins (e.g. collagens, elastin and laminins) and proteoglycans (e.g. perlecan). Matrix metalloproteinases (MMPs), cathepsins and bone-morphogenet...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-02-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00011/full |