Matricryptins network with matricellular receptors at the surface of endothelial and tumor cells

The extracellular matrix is a source of bioactive fragments called matricryptins or matrikines resulting from the proteolytic cleavage of extracellular proteins (e.g. collagens, elastin and laminins) and proteoglycans (e.g. perlecan). Matrix metalloproteinases (MMPs), cathepsins and bone-morphogenet...

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Bibliographic Details
Main Authors: Sylvie eRICARD-BLUM, Sylvain Daniel Vallet
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00011/full