Formulation and evaluation of a bioadhesive patch for buccal delivery of tizanidine
Tizanidine hydrochloride (THCl) is an antispasmodic agent which undergoes extensive first pass metabolism making it a possible candidate for buccal delivery. The aim of this study was to prepare a monolayered buccal patch containing THCl using the emulsification solvent evaporation method. Fourteen...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-06-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383512000287 |