Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids, such as triacylglycerol (TG), as reservoirs of metabolic energy and membrane precursors. The Arf1/COPI protein machinery, known for its role in vesicle trafficking, regulates LD morphology, targeting of specific proteins to LD...

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Bibliographic Details
Main Authors: Florian Wilfling, Abdou Rachid Thiam, Maria-Jesus Olarte, Jing Wang, Rainer Beck, Travis J Gould, Edward S Allgeyer, Frederic Pincet, Jörg Bewersdorf, Robert V Farese Jr, Tobias C Walther
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-02-01
Series:eLife
Subjects:
lipid droplet
protein targeting
ER-lipid droplet connection
lipolysis
triglyceride synthesis
Online Access:https://elifesciences.org/articles/01607

Internet

https://elifesciences.org/articles/01607

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