Key hub and bottleneck genes differentiate the macrophage response to virulent and attenuated Mycobacterium bovis

Key hub and bottleneck genes differentiate the macrophage response to virulent and attenuated Mycobacterium bovis

Mycobacterium bovis is an intracellular pathogen that causes tuberculosis in cattle. Following infection, the pathogen resides and persists inside host macrophages by subverting host immune responses via a diverse range of mechanisms. Here, a high-density bovine microarray platform was used to exami...

Full description

Bibliographic Details
Main Authors: Kate E. Killick, David A. Magee, Stephen D. E. Park, Maria eTaraktsoglou, John A. Browne, Kevin M. Conlon, Nicolas C. Nalpas, Eamonn eGormley, Stephen V. Gordon, David E. MacHugh, Karsten eHokamp
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Immunology
Subjects:
Cattle
Mycobacterium bovis
Tuberculosis
network
macrophage
BCG
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00422/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00422/full

Similar Items