Porous Scaffolds Support Extrahepatic Human Islet Transplantation, Engraftment, and Function in Mice

Islet transplantation as a therapy or cure for type 1 diabetes has significant promise but has been limited by islet mass requirements and long-term graft failure. The intrahepatic and intravascular site may be responsible for significant loss of transplanted islets. Nonencapsulating biomaterial sca...

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Bibliographic Details
Main Authors: Romie F. Gibly, Xiaomin Zhang, William L. Lowe, Lonnie D. Shea
Format: Article
Language:English
Published: SAGE Publishing 2013-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X636966