Focus on Hypoxia-Related Pathways in Pediatric Osteosarcomas and Their Druggability

Focus on Hypoxia-Related Pathways in Pediatric Osteosarcomas and Their Druggability

Osteosarcoma is the most frequent primary bone tumor diagnosed during adolescence and young adulthood. It is associated with the worst outcomes in the case of poor response to chemotherapy and in metastatic disease. While no molecular biomarkers are clearly and currently associated with those worse...

Full description

Bibliographic Details
Main Authors: Marina Pierrevelcin, Quentin Fuchs, Benoit Lhermitte, Melissa Messé, Eric Guérin, Noelle Weingertner, Sophie Martin, Isabelle Lelong-Rebel, Charlotte Nazon, Monique Dontenwill, Natacha Entz-Werlé
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
osteosarcoma
hypoxia
progression
immunity
druggability
preclinical models
Online Access:https://www.mdpi.com/2073-4409/9/9/1998

Internet

https://www.mdpi.com/2073-4409/9/9/1998

Similar Items